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The Chemical Educator

ISSN: 1430-4171 (electronic version)

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Abstract Volume 5 Issue 3 (2000) pp 144-144

Heteropolyacid-Catalyzed Synthesis of Aspirin

Yanqing Peng, and Gonghua Song*

Institute of Pesticides and Pharmaceuticals, East China University of Science and Technology, Shanghai 200237, P. R. China

Published online: 1 June 2000

Abstract. Aspirin was synthesized from salicylic acid and acetic anhydride in the presence of noncorrosive 12-tungstophosphoric acid as an alternative catalyst to liquid acids, e.g., sulfuric acid. This process can be carried out at room temperature and gives a reasonable yield of isolated product.

Key Words:  Laboratories and Demonstrations; general chemistry

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Issue date: June 1, 2000

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