A Streamlined Combinatorial Esterification

TCE

The Chemical Educator

ISSN: 1430-4171 (electronic version)

Table of Contents

Abstract Volume 8 Issue 6 (2003) pp 352-352

A Streamlined Combinatorial Esterification

Christine R. Whitlock* and Patricia A. Bishop

Department of Chemistry, Georgia Southern University, Statesboro, GA, 30460, cwhitlock@georgiasouthern.edu
Received May 26, 2003. Accepted August 8, 2003.

Published online: 25 October 2003

Abstract. An experiment demonstrating combinatorial chemistry is described. Individual students prepare nine esters from three carboxylic acids and three alcohols. These esters are then “screened” by their fragrances.

Key Words: Laboratories and Demonstrations; organic chemistry; combinatorial synthesis; Fischer esterification

(*) Corresponding author. (E-mail: cwhitlock@georgiasouthern.edu)

Article in PDF format (141 KB) HTML format

Supporting Materials:

Notes to the instructor and a student handout with the detailed procedure are available in both Microsoft word and PDF formats for download in a Zip file (114 KB) 10.1333/s0089703735.