The Chemical Educator
ISSN: 1430-4171 (electronic version)
Abstract Volume 9
Issue 1 (2004) pp 27-29
Multi-Week Synthesis of a Sunscreen Agent for the Organic Chemistry Laboratory
Gary W. Breton* and Melanie K. Belk
Berry College, Department of Chemistry, PO Box 495016, Mount Berry,
GA 30149, email@example.com
Published online: 22 January 2004
Abstract. A multi-week laboratory experiment on the synthesis of the sunscreen agent octyl 4-methoxycinnamate is presented. The synthesis of the compound illustrates the usefulness of three important synthetic methods typically encountered in the second semester of a traditional organic chemistry course. Reasonable-to-good average yields were obtained for each of the synthetic steps by our organic chemistry laboratory students. The effectiveness of the synthesized sunscreen was evaluated utilizing UV–vis spectroscopy.
Key Words: Laboratories and Demonstrations; organic chemistry
(*) Corresponding author. (E-mail: firstname.lastname@example.org)
Experimental procedure for the synthesis of the intermediate, methyl methoxycinnamate (2), a student handout for the laboratory experiment, and copies of relevant 1H NMR spectra are available in a Zip file (458 KB).
Issue date: February