The Chemical Educator
ISSN: 1430-4171 (electronic version)
Abstract Volume 9
Issue 1 (2004) pp 30-31
A Solvent-free Oxidation of 1-Pentanol to Pentanoic Acid for the Undergraduate Organic Laboratory
Jaclyn A. Barrett, John J. Esteb,* Geoffrey C. Hoops, and Jeremy M. Richter
Butler University, Clowes Department of Chemistry, 4600 Sunset Avenue,
Indianapolis, Indiana 46208, email@example.com.
Published online: 9 January 2004
Abstract. Herein we present an oxidation experiment for a first-year organic chemistry class. This oxidation utilizes a solid mixture of CuSO4·5 H2O and KMnO4 prepared by the students using a mortar and pestle. The oxidation takes place under solvent-free conditions and a good yield is obtained for the reaction. This experiment provides for the simple oxidation of a primary alcohol to a carboxylic acid using a relatively nontoxic oxidizing agent under solvent-free conditions. Furthermore, students are able to utilize acid–base extraction techniques for purification of the final product.
Key Words: Laboratories and Demonstrations; organic chemistry; organic synthesis; laboratory instruction; oxidation reactions; solvent-free
(*) Corresponding author. (E-mail: firstname.lastname@example.org)
A laboratory handout out for students is available (26 KB zip file).
Issue date: February