The 2008 Nobel Prize in Chemistry: Osamu Shimomura, Martin Chalfie, and Roger Y. Tsien : the Green Fluorescent Protein

TCE

The Chemical Educator

ISSN: 1430-4171 (electronic version)

Table of Contents

Abstract Volume 14 Issue 2 (2009) pp 70-78

The 2008 Nobel Prize in Chemistry: Osamu Shimomura, Martin Chalfie, and Roger Y. Tsien : the Green Fluorescent Protein

George B. Kauffman* and Jean-Pierre Adloff

Department of Chemistry, California State University, Fresno, Fresno, CA 93740-8034, georgek@csufresno.edu, Honorary Professor, Université Louis Pasteur, 63 Rue Saint Urbain, Strasbourg, France F-67100, jp.adloff@noos.fr

Published online: 1 April 2009

Abstract. The 2008 Nobel Prize in Chemistry was awarded equally to the Japanese Osamu Shimomura and the Americans Martin Chalfie and Roger Y. Tsien “for the discovery and development of the green fluorescent protein GFP.” Relevant research by the laureates and others, especially Douglas Prasher, is discussed along with applications of their work.

Key Words: Chemistry and History; Green Fluorescent Protein (GFP); Nobel Prize; Self-luminescence; Aequorin; Aequoria victoria; Jellyfish; Corals; Genetic Tags; Cell Biology; Genetics; “Brainbow.”

(*) Corresponding author. (E-mail: georgek@csufresno.edu)

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