TCE

The Chemical Educator

ISSN: 1430-4171 (electronic version)

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Abstract Volume 19 (2014) pp 241-246

Investigation of ¹H NMR Chemical Shift in Various Systems: A Set of Advanced 1D ¹H NMR Undergraduate Laboratory Projects

Laurie A. Witucki, William R. Winchester and Shannon M. Biros*

Department of Chemistry, Grand Valley State University, Allendale, MI 49401, biross@gvsu.edu
Received May 13, 2014. Accepted June 26, 2014.

Published: 20 July 2014

Abstract. A set of five advanced undergraduate experiments teaching specialized 1D ¹H NMR topics is presented. The organization of these laboratory projects is such that students carry out one experiment then teach the concepts covered to the rest of the class through brief oral presentations of their data. Student learning is assessed through a written report where students must analyze and explain all five experiments. With this arrangement, five distinct topics in ¹H NMR are covered in depth in one or two laboratory meetings, compared to five separate sessions. The projects contained here illustrate the interpretation of spectra from compounds with exchangeable protons, intramolecular hydrogen bonding, keto-enol tautomers and the use of lanthanide shift reagents. References to supplemental experiments are included so instructors can select the experiments and depth of analysis based on laboratory time, NMR instrumentation, student background and class size.

Key Words: Laboratories and Demonstrations; organic chemistry; NMR Spectroscopy; hands-on/active learning; lanthanide shift Reagent (LSR); exchangeable hydrogens; keto-enol tautomerism

(*) Corresponding author. (E-mail: biross@gvsu.edu)

Article in PDF format (275 KB) HTML format

Supporting Materials:

Procedures for student experiments, sample lab reports, notes for the instructor, and copies of all ¹H NMR spectra are available (2.72 MB).

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