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The Chemical Educator

ISSN: 1430-4171 (electronic version)

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Abstract Volume 20 (2015) pp 4-5

Microwave-Induced Synthesis of 3-Unsubstituted β-Lactams Via Radical-Mediated Reaction

Sunena Chandra, Ram N. Yadav, Laraib Safeer and Bimal K. Banik*

Department of Chemistry, University of Texas-Pan American, 1201 W. University Dr., Edinburg, TX 78539, USA,
Received May 13, 2014. Accepted September 27, 2014.

Published: 16 January 2015

Abstract. A facile method for the preparation of 3-unsubstituted β-lactams is developed via tributyltin hydride-induced reaction of the corresponding xanthates.

Key Words: Laboratories and Demonstrations; organic chemistry; β-lactam; azo-isobutyronitrile; tributyltin hydride; xanthate; anti-cancer; microwave

(*) Corresponding author. (E-mail:

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