An Advanced Undergraduate Experiment in 2-D NMR

TCE

The Chemical Educator

ISSN: 1430-4171 (electronic version)

Table of Contents

Abstract Volume 3 Issue 4 (1998), S1430-4171(98)04229-6

An Advanced Undergraduate Experiment in 2-D NMR

James L. Roark and Michael D. Mosher*

Department of Chemistry, University of Nebraska at Kearney, Kearney, NE 68849-1150

Published online: 3 August 1998

Abstract. The concurrent use of one-dimensional (¹H-NMR) and two-dimensional (¹H-¹H-COSY and ¹H-¹H-Delay-COSY) experiments can unambiguously assign each resonance in a spectrum to a particular proton. We have developed an experiment for the advanced chemistry student that utilizes long-range coupling to assign signals in the spectra of ketopinic acid, borneol, and isoborneol. Prelaboratory discussion of the spectra of camphor, hands-on use of the instrumentation, and determination of molecular stereochemistry are topics visited during the course of this experiment.

Key Words: Laboratories and Demonstrations; laboratory; NMR; COSY; camphor; borneol; ketopinic acid; isoborneol; coupling

(*) Corresponding author. (E-mail: mosherm@platte.unk.edu)

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